Organization Profile
Prisma Health-Upstate is an organization based in Simpsonville, SC and listed in the NPI registry under general acute care hospital. NPI 1447706569 identifies this record in the national registry.
Factual summary compiled by Guide.md from public records; not written by this provider.
Counted from individual NPI records registered at the same street address; a shared building can inflate this.
From registry street addresses: providers filed at this building, which can include unrelated practices sharing it.
Source: CMS Care Compare, Hospital General Information, checked 2026-09-12.
375 Medicare discharges across 16 diagnosis groups (2024). Groups with fewer than 11 discharges are not published by CMS.
| Diagnosis group | DRG | Discharges | Avg. Medicare payment |
|---|---|---|---|
| Septicemia Or Severe Sepsis Without Mv >96 Hours With Mcc | 871 | 96 | $8,851 |
| Heart Failure and Shock With Mcc | 291 | 59 | $6,398 |
| Kidney and Urinary Tract Infections Without Mcc | 690 | 26 | $3,515 |
| Septicemia Or Severe Sepsis Without Mv >96 Hours Without Mcc | 872 | 21 | $4,749 |
| Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders Without Mcc | 392 | 21 | $3,376 |
| Respiratory Infections and Inflammations With Mcc | 177 | 20 | $7,808 |
| Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes With Mcc | 640 | 17 | $6,047 |
| Kidney and Urinary Tract Infections With Mcc | 689 | 16 | $5,614 |
| Other Kidney and Urinary Tract Diagnoses With Mcc | 698 | 14 | $8,343 |
| Renal Failure With Mcc | 682 | 14 | $8,394 |
Source: CMS Medicare Inpatient Hospitals by Provider and Service. Shows what the hospital admits Medicare patients for and what Medicare paid on average — not quality of care.
729 SE MAIN ST
Simpsonville, SC 29681
This rating is published by the Centers for Medicare & Medicaid Services (CMS) and is reproduced here unmodified.
Prisma Health-Upstate is a hospital in Simpsonville, SC. That is the designation recorded for this NPI in the federal registry, where it is listed as “General Acute Care Hospital”.
NPI registry
Prisma Health-Upstate is listed at 729 Se Main St, Simpsonville, SC 29681. Addresses come from the NPI registry and can lag a move, so confirm before travelling.
NPI registry
The number on file is (864) 454-3100. Contact the office directly to confirm availability and scheduling.
NPI registry
Prisma Health-Upstate's National Provider Identifier is 1447706569. It is issued by the Centers for Medicare & Medicaid Services and is unique and permanent — it does not change if they move practice.
NPI registry
Not yet. This profile is built from public federal data and has not been confirmed by Prisma Health-Upstate. If this is you, claiming it is free.
Guide.md
Manage this listing? Log in or create an account, then click “This is my practice and I manage it” here. A verified physician whose registry address matches this location is approved instantly; everyone else is reviewed by a person.
Guide.md listings do not constitute medical advice or an endorsement.