Organization Profile
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From registry street addresses: providers filed at this building, which can include unrelated practices sharing it.
License numbers are what the provider reported to NPPES when the NPI was issued or updated. NPPES does not verify licensure; confirm current standing with the state licensing board.
Source: CMS Care Compare, Hospital General Information, checked 2026-09-12.
375 Medicare discharges across 16 diagnosis groups (2024). Groups with fewer than 11 discharges are not published by CMS.
| Diagnosis group | DRG | Discharges | Avg. Medicare payment |
|---|---|---|---|
| Septicemia Or Severe Sepsis Without Mv >96 Hours With Mcc | 871 | 96 | $8,851 |
| Heart Failure and Shock With Mcc | 291 | 59 | $6,398 |
| Kidney and Urinary Tract Infections Without Mcc | 690 | 26 | $3,515 |
| Septicemia Or Severe Sepsis Without Mv >96 Hours Without Mcc | 872 | 21 | $4,749 |
| Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders Without Mcc | 392 | 21 | $3,376 |
| Respiratory Infections and Inflammations With Mcc | 177 | 20 | $7,808 |
| Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes With Mcc | 640 | 17 | $6,047 |
| Kidney and Urinary Tract Infections With Mcc | 689 | 16 | $5,614 |
| Other Kidney and Urinary Tract Diagnoses With Mcc | 698 | 14 | $8,343 |
| Renal Failure With Mcc | 682 | 14 | $8,394 |
Source: CMS Medicare Inpatient Hospitals by Provider and Service. Shows what the hospital admits Medicare patients for and what Medicare paid on average — not quality of care.
727 SE MAIN ST STE 180
Simpsonville, SC 29681
This rating is published by the Centers for Medicare & Medicaid Services (CMS) and is reproduced here unmodified.
Prisma Health-Upstate is a hospital in Simpsonville, SC. That is the designation recorded for this NPI in the federal registry, where it is listed as “General Acute Care Hospital”.
NPI registry
Prisma Health-Upstate is listed at 727 Se Main St Ste 180, Simpsonville, SC 29681. Addresses come from the NPI registry and can lag a move, so confirm before travelling.
NPI registry
The number on file is (864) 455-7000. Guide.md cannot book appointments or pass on messages — please call the office directly.
NPI registry
Prisma Health-Upstate's National Provider Identifier is 1003626326. It is issued by the Centers for Medicare & Medicaid Services and is unique and permanent — it does not change if they move practice.
NPI registry
Not yet. This profile is built from public federal data and has not been confirmed by Prisma Health-Upstate. If this is you, claiming it is free.
Guide.md
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Provider data sourced from the NPPES NPI Registry and CMS public datasets. Information is provided for reference and is not medical advice.